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This is just one of the tools generated through the Multiple Sclerosis Outcome Assessments Co dunk nike low nsortium (MSOAC), a global effort launched by the National MS Society and Critical Path Institute (C-Path). MSOAC is striving to develop an outcomes measure that addresses the critical need for a more sensitive way to detect the benefit of potential treatments that slow or reverse progressive disability in people with MS.鈥淜ey to the success of every C-Path consortium is the sharing of exp adidas yeezy ertise and data,鈥?stated Lynn Hudson, PhD, C-Path鈥檚 Chief Science Officer and Executive Director of af1 MSOAC. 鈥淭he sharing of both treatment and placebo arm data by MSOAC member companies is unparalleled.鈥漀early 15,000 records from active treatment and inactive placebo arms, a rich source of performance measures and related clinical information, are currently being analyzed for regulatory qualification of a new instrument to measure disability and progression in MS. The measurement tool, which will also incorporat CAPE TOWN:David Warner h adidas campus bianche it a magnificent century for Austr newbalance 574 alia but could not prevent South Africa from completing a clean sweep by winning the fifth and final ODI by 31 runs at Newlands on Wednesday.Warner hit 173 off 136 balls but received scant support from his teammates as Australia, chasing South Africa鈥檚 327 for eight, were bowled out for 296.South Africa won all five matches in the series, the first time Australia have suffered such a beating in a five-game bilateral series. However, Australia will retain their number one ranking in ODIs, with South Africa two points behind in second place.鈥淒avid was phenomenal but the rest of us didn鈥檛 stand up,鈥?said Australian captain Steve Smith. 鈥淐redit to South Africa, we鈥檝e been outplayed in all the games.鈥漇outh Africa name uncapped spin duo for Australia tourRilee Rossouw hit 122 and JP Duminy made 73 as South Africa piled up the third-highest to new balance tal in an ODI at Newlands, making them firm favourites on a ground where the highest successfu

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Each year there are more than three million cases of cholera worldwide, a disease transmitted through contaminated food and water that hits developing countries particularly hard. While the sta yeezys 350 ndard regimen for protecting against cholera with existing non-living oral cholera vaccines includes ad yeezy 700 ministering two doses over a two-week period, research at the University of Maryland School of Medicine (UMSOM) now shows that giving a stronger single-dose of a live oral vaccine could be an effective tool in controlling outbreaks more quickly.Th dunk low e UMSOM research, published in Clinical and Vaccine Immunology, was conducted in Mali and included 150 participants. Researchers assessed the effectiveness (ability to stimulate vibriocidal antibody, an immune response that correlates with protection) of a single high-dose of live cholera vaccine CVD 103-HgR, which was developed by UMSOM鈥檚 Center for Vaccine Development (CVD) and licensed and manufactured by PaxVax, versus the standard two-dose killed v LONDON:Roberto di Matteo is the new manager of Aston Villa, the former English champions said on their website on Friday.The 46-year-old Italian, who won the Champions League during a short spell in charge of Chelsea, takes over weeks after the club were relegated from the Premier League.鈥淚t鈥檚 a wonderful honour for me to become manager of this great football club, and I鈥檓 looking forward to the challenge of taking Aston Villa back to its rightful place,鈥?Di Matteo said.Villa relegated nb zapatillas as Sund adidas campus damen new balance rosa erland, Newcastle boost survival hopesVilla endured a dreadful season, sacking manager Tim Sherwood in October as well as his replacement Remi Garde in March.

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Rhiu May meets Trump with eye on Brexit future
A new mRNA vaccine targeting immune cells in the liver could be the key to tackling malaria, a disease that causes ove yeezy 500 r half a million deaths each year according to the World Health Organization, yet has no effective long-lasting vaccine.Trans-Tasman research collaborators from Te Herenga Waka鈥?Victoria Universit new balance f眉r damen y of Wellington鈥檚Ferrier Research Instituteand theMalaghan Institute of Medical Researchin New Zealand, and thePeter Doherty Institute for Infection and Immunityin Australia have developed an mRNA-based vaccine that can effectively target and stimulate protective immune cell responses against the malaria-causing parasitePlasmodiumin preclinical models.Want more breaking news?Subscribe to Technology Networks鈥?daily newsletter, delivering breaking dunk low science news straight to your inbox every day.Subscribe for FREE Action shots by Brazilian local聽Luiz Claudio captured a stunning jaguar cooling off with a drink from a river when it met with a smaller predator.聽Much to his surprise, the聽220lb cat took down a crocodile, at adidas campus rosa tac stanley cup ked it and dragged it away, all of which Claudio managed to capture while passing by.The predator proved its prowess with stealth and brute force as it wrestled with the crocodile in the water, before taking control and delivering the fatal blow by biting the back of the croc's neck. Paws for a drink: A jaguar who decided to cool off with a drink from a Brazilian river came back with more than it bargained for as it picked up a crocodile for boots kaufen lunch.

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Jjap Shaukat Thanvi: A cultured satirist
GE Healthcare Life Sciences will open a Technology and Training Laboratory to support Turke chanclas yeezy y鈥檚 expanding biopharmaceutical and biotechnology industry. A key component of GE鈥檚 Turkey Innovation Center in Istanbul, the laborat nike air forces 1 ory will open to customers, industry and academic partners from m nike dunks panda id-2015. This adds to GE鈥檚 global network of biopharmaceutical customer training and technology facilities in the US, UK, China, India and Sweden.The GE Healthcare Life Sciences Technology Laboratory will feature the company鈥檚 latest tools and technologies for drug discovery, protein science, and bioprocessing research. It will offer advanced technical training and technology evaluation to the Turkish biopharmaceutical sector, as well as being open to universities as a location for elements of biotechnology degree courses. Academics, pharmaceutical and biotechnology researchers will also have access to the laboratory for small scale research studies using the latest GE equipment, as will GE customers f KABUL:Afghan president Ashraf Ghani on Monday welcomed as an "achievement" the renewed funding commitment from NATO for his country's fledgling security forces amid in new balance homme creasing Taliban insurgency.On Saturday NATO countries agreed at a summit in Warsaw to adidas campus pink maintain troop numbers in Afghanistan and reiterated a funding pledge of $5 billion a year for local security forces until 2020.Pakistan urges Afghanistan to capitalise on success of Zarb-e-Azb"Afghanistan returned successfully from the Warsaw summit and I congratulate the nation for that," Ghani told reporters in Kabul."We achieved what we wanted to achieve and we are thankful to the world for that," he said.About 12,000 NATO troops, of which the bulk are American, are currently stationed in Afghanistan under Operation Resolute Support, to train and assist Afghan security forces.But the Afghans have struggled to contain a resurgent Taliban and have suffered brutal losses -- more than 5,000 local police and troops were killed in adidas campus 80s 2015, a

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Ompd Minor remanded for killing younger sister in Lahore
In a world first, researchers from Penn Medicine have used genetically yeezy modified T cells to target and ablate fibroblasts that contribute to the development of heart disease.What is CAR-T cell therapy?CAR-T cell therapy is a relatively novel form of immunotherapy that is being used to treat certain ty dunk nike pes of cancer, primarily blood cance yeezy foam rs. A form of adaptive cell transfer (ACT), CAR-T cell therapy involves genetically modifying a patient's own T cells in the laboratory.The T cells are extracted from the patient's blood, and the gene for a chimeric antigen receptor (CAR) is inserted. These receptors are "synthetic", meaning they do not exist naturally.The CAR is expressed on the cell surface of the T cell and enables the immune cell to recognize specific antigens expressed in cancer cells. Thus, when the T cells are infused back into the patient, they target and kill the cancer cells. ISLAMABAD:Inspector General of the Islamabad Police(IGP) Tariq Masood Yaseen has appreciated the security personnel and officers for ensuring elab newbalance 9060 orate security arrangements in the city during Eidul Fitr to avoid any untoward incident.He expressed these views while addressing the police, FC and Rangers personnel, including officers adidas samba donna , at a luncheon arranged at Police Lines in Islamabad. The event was attended by Islamabad Chief Commissioner Zulifq ugg mini ar Haider, AIG Special Branch Waqar Chohan, SSP Security Mir Wais Niaz, SSP Operations Sajid Kiani, SSP Headquarter Muhammad Bin Ashraf and others.The IGP hoped that the Islamabad Police would continue its efforts to protect the lives and property of citizens, saying, 鈥淲e have to move forward to improve our performance in accordance of the vision of Interior Minister Chaudhry聽 Nisar Ali Khan to make the capital crime free.鈥漈he Islamabad Police, he said, would not forget its 39 martyrs who sacrificed their lives for protection of lives and proper

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Qfmt Lok Mela: Folk sights, sounds of Pakistan
Cancer researcher Rita Fior uses zebrafish to study human cancer. Though this may seem like an unlikely match, her work shows great promise with forthcoming applications in personalised medicine.The basic principle of Fior's appro converse schuhe ach relies on transplanting human cancer cells into dozens of zebrafish larvae. The fish then serve as "living test tubes" where various treatments, such as different chemotherapy drugs, can be tested to reveal which works best. The assay i dunk s rapid, producing an answer within four short days.Some years ago, when Fior was developing this assay, she noticed something curious. "The majority of human tumour cells successfully engrafted in the fish, but some tumours didn't. They would just disappear within a day or two. However, when I treated the transplanted fish with adidas yeezy chemotherapy, these tumors would not disappear anymore. They engrafted much more", she recalls.This seemingly paradoxical observation triggered a new working hypothesis. "Chemotherapy suppresses the KARACHI:The world of pro wrestling is full of as much unbelievable stories backstage as it is with crazy stories on-screen. Much of the life of wrestlers revolves around travelling from city to city to perform and life on the road exposes them to ridiculous to outright bizarre situations.Internet is full of stories from wrestlers鈥?lives that some would believe to be lies. But upon years or telling and retelling of some stories, these stories have become legends. And if you鈥檝e ever wondered what these macho men are like adidas campus bianche in real lives, look no further. We bri new balance 480 ng you some of the craziest, funniest and even the most ridiculous real life stories from the unique world of professional wrestling.Ex-WWE stars among 25 wrestlers coming to Pakistan this MayRic Flair survives plane crashHow many people can claim they survived a plane crash? Flair is one of the only few luckiest guns adidas campus rouge alive to have walked out of a plane crash. On October 4, 1975, a Cessna 310 plane carrying a promoter and four wrestl

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Pdji Property Dispute: Man shot dead in Haripur
Through a collaborative effort, researchers have developed a novel compound with the ability to inhibit melanoma cell growth. This research, published today in Nature Communications, could pave the way for the development of a new class of cancer therapies, with improved safety and efficacy.The term 鈥榚pigenetics鈥?is used to def dunk nike low ine the molecular processes that influence changes in gene expression, without directly affecting the original DNA sequence. The body is yeezy slide able to turn genes 鈥榦n鈥?or 鈥榦ff鈥?via epigenetic changes. These changes can result in cellular modifications that can lead to the conversion of a cell from 鈥榥ormal鈥?to 鈥榗ancerous鈥? and can also promote a tumor鈥檚 growth and resistance to treatment. The novel compound 鈥楥orin鈥?can target specific epigenetic modifying proteins. Through this mechanism, it could be possible to significantly improve a patient鈥檚 condition, without unwanted adverse effects. The clinical use of epigenetic drugs is currently limited d nike air forces ue to their limited the Two very different people, at very different stages of their lives, at the end of their careers in very different ways, gave one hope for the future of Pakistan. While people celebrate one and mourn the other, I would like to hail them both as beacons of light.The first is General Raheel Sharif, who not only achieved a lot during his career but set a precedent for ending the career that would force those to come to follow in his footsteps. He new balance 740 took the battle against 鈥渢he enemy within鈥?to their doorstep and began the process of ridding our poor country of this menace. Though many have paid lip service to the cause, none went boldly forward to do what needed to be done. They say that 鈥淧ower corrupts; and absolute power corrupts absolutely鈥? In Pakistan, as Chief of Army Staff, absolute power was his for the taking, but he decli newbalance 550 ned to go near it and went on to declare that adidas original campus he would take no extension of his term. Despite popular sentiment, when thrice offered 鈥渢he kingly crown, He did thri

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Znrv Big Data Drills Down Into Metabolic Details
Genomic sequencing experts at Johns Hopkins partnered with pharmacologists at Stony Brook University to reveal a striking mutational signature of upper urinary tract cancers caused by aristolochic acid, a plant compound contained in herbal remedies used for thousands of years to treat a variety of ailments such as arthritis, gout and inflammation. Their discovery is described in the Aug. 7 issue of Science Translational Medici yeezys 350 ne.Aristolochic [pronounced a-ris-to-lo-kik] acid is yeezy found in the plant family "Aristolochia," a vine known widely as birthwort, and while the U.S. Foo nike dunk nike d and Drug Administration first warned of its cancer-causing potential in 2001, botanical products and herbal remedies containing it can still be purchased online. Moreover, the vine has been found to be an environmental carcinogen through the contamination of food supplies of farming villages in the Balkans, where Aristolochia grows wildly in the local wheat fields. For years, scientists have known of some mutation If you still don't know who Mariam Saleem Nawaz 聽is, you must be living under a rock.The youngster has become an overnight sensation, thanks to her hilarious description of wh adidas campus wei脽 at going to a desi beauty parlour entails.London cosmetics firms fined for selling Pakistani skin whitening creamsMariam has used Snapchat filters聽to her advantage in her video and truly managed to strike a chord with a campus adidas ny woman who has ever been to a parlous in Pakistan or India. She's sure to have you nodding your head in agre uggs ement.Have a look for yourself here[fbpost link="https://www.facebook.com/24bitOgglywash/posts/10155078809566584"]Have something to add to the story? Share it in the comments below.

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Bmhl Inside the consulate: Afghan diplomat shot dead in Karachi
As you're driving to work along a busy road, your eyes on the traffic lights ahead, hoping they won't turn to red, you pass signs warning of roadworks, ads on bus shelters... Suddenly a dog runs out in front of you. What are your chances of seeing it before it' yeezy 350 s too late?Even with 20/20 vision in broad daylight on a clear day, our peripheral vision can be surprisingly poor, particularly when the scene in front of us is cluttered. Now, scientists at the University of Cambridge, UK, Northeastern University, Boston, USA, and Queensland Brain Institute, Brisbane, Australia, believe they are a step closer to understanding why this is."When objects in our peripheral vision are surrounded by visual clutter, a phenomenon known as 'visual crowding' hinders our ability to make sense of wha yeezy 500 t we see," explains Will Harrison dunk nike store from the University of Cambridge. "Visual crowding is ubiquitous in natural scenes and affects virtually all everyday tasks, including readin ISLAMABAD:An independent economist has questioned an international report on poverty incidence in Pakistan, which says that only 3.1 per cent of the population live in poverty in the federal capital, the lowest as compared to other cities and districts of the country.The federal capital is followed by two provincial capitals ?€? Lahore and Karachi ?€? w ugg hausschuhe here the poverty newbalance ratio is 4.3 and 4.5 per cent, respectively.Only half a dozen districts in the country fell within the single-digit poverty ratio category.?€?The figures do not reflect the actual situation on the ground since the studies are relative,?€? Dr Kaiser Bengali, and independent economist says.St stanley kaufen atistics measured according to the multidimensional poverty index (MPI), show that Islamabad is the city of the rich, with only 3.1 per cent of its population categorised as poor.However, Bengali says that if Islamabad was compared to world capitals, the situation might not look too encouraging.?€?Capitals usually finish higher in such comparati

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Rvls Investment finance services: SECP issues first licence
With nearly breakneck speed, the demands of work productivity in today鈥檚 society seem to have increased tenfold. Enter multitasking jordans damen as a way to cope with the insistence that tasks be completed almost immediately. Previous studies on workload and productivity include physical aspects, such as how much a person walks or carries, but they do not take into account a person鈥檚 state of mind. Now, MU researchers have discovered a person鈥檚 eyes may offer a solution.鈥淚f your vitals are bad, then something is wrong with your body and doctors will work to figure out what鈥檚 wrong wi adidas yeezys th you,鈥?said Jung Hyup Kim, an assistant professor of industrial and manufacturing systems engineering in the MU College of Engineering. 鈥淲hat about your mental health? Many people multitask, but currently there is no measurement for someone鈥檚 mental well-being. However, we found that the size of a pupil could be the key to measuring someone鈥檚 mental state while they multitask.鈥滶veryone experiences stress differen dunk nike high tly. CHICHAWATNI:A retired police official was gunned down while his associate was injured by rivals over an old enmity in Iqbal Nagar area of Chichawatni on Wednesday.Of adidas velosamba ficials said Jehangir Kathia and his associate Zulfiqar Kathia were on their way to Multan to attend a case hearing when members of their rival group Zaheer Kathia, Nasir and Azhar opened indiscriminate fire on them.Policeman arrested for 'raping' complainantAs a result, Jehangir Kathia was killed on the spot while Zulfiqar suffered injuries. Rescue officials shifted the body and the injured to Tehsil Headquarters Hospital for treatment.A police official said the armed suspects managed to escape from the scene. He added the police were conducting raids to arrest the culprits. He maintained the incident t newbalance 530 ook place due to an old enmity between the two rival groups.Police officer beaten to death in Indian-occupied KashmirEarlier, a nb 9060 station house officer among two policemen was killed in a shooting incident in Faisalabad. The i

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Pbhy Karachi operation: Eight ;criminals; taken into custody
Strategic Diagnostics Inc. has announced that it has signed an agreement to su dunk nike low pply bio-reagents to a large manufacturer of in-vitro diagnostics. The initial term of the agreement is five years. Starting revenues are estimated at $1 million per year and are anticipated to more than double over the term of the agreement. Strategic Diagnostics will begin shipping bio-reagents to the customer in the fourth quarter of 2006. "Contract production of bio-reagents through our Strategic BioSolutions鈩?brand is a core competency of Strategic Diagnostics Inc.," commented Matt Knight, President and CEO. "We have a relationship based on well-demonstrated and proven capabilities with our customer, which has now significantly extended the scope of business through this agreement.""During the past two years, the SDI team has worked tirelessly to secure contracts like thi nike dunk high s one through process improve nb sneakers 574 ment and technical innovation.""Process improvements throughout the value chain assure the highest quality Pakistan Tehreek-s-Insaf (PTI) chairperson Imran Khan聽has said that military operation should be carried out in the聽entire country simultaneously."No extremist organisation should be allowed to operate in the country," said Imran, while addressing a press conference in Islamabad on Thursday.Imran t adidas samba sale ermed it condemnable that terrori stanleycup st attacks were taking place again. "We need to change policies which previously allowed such organisations to operate," he said.Army mounts n adidas samba vegan ew nationwide offensive"All political parties had mutually signed the National Action Plan (NAP) and it should have been implemented in letter and spirit," Imran said.Regarding the ongoing Panama Papers hearing at the Supreme Court, Imran said, "This is a defining moment for Pakistan, the country is changing."On Thursday, the apex court reserved its decision in the case against the Sharif family鈥檚 alleged offshore wealth in London."Pakistan is engaged in this case for the last eight months and the country is now changing

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Scdp Who s Responsible for All the Roadside Rubbish
Bite size depends on the familiarly and texture of food. Smaller bite sizes are taken for foods which need more chewing and smaller bite sizes are often linked to a sensatio dunk panda n of feeling fuller sooner.New research published in BioMed Central鈥檚 open access journal Flavour, launched, shows that strong aromas lead to smaller bite sizes and suggests that aroma may be used as a means to control portion size.The aroma experience of food is linked to its constituents and texture, but also to bite size. Smaller bites sizes are linked towards a lower flavour release which may explain why we take smaller bites of unfamiliar or disliked foods.In order to separa converse all star te the effect of aroma on bite size from other food-related sensations researchers from the Netherlands developed a system where a custard-like dessert was eaten while different scents were simultaneously presented directly to the participants nose.The results showed tha dunk high t the stronger the smell the smaller the bite. Dr Rene A de Wijk, who le After days of uncertainty and failed negotiations with several candidates, South Africa- born Mickey Arthur has been handed over the reins of Pakistan cricket. The 47-year-old replaces Waqar Younis as the head co adidas schuhe campus ach of the most mercurial adidas samba og team in international cricket. Arthur has rich coaching experience at both the franchise and highest levels of the game, with his most high-profile stints including coaching the national teams of South Africa and newbalance 990 Australia. These were largely successful spells but had their share of controversies. Arthur was one of the first coaches in international cricket to openly embrace technology, bringing about a revolution in cricket coaching. He is considered to be a tactically smart coach who relies extensively on data collection and analysis of strengths and weaknesses of both his side as well as the rivals across the three formats.Besides international teams, Arthur has coached extensively at the franchise level, which also included a stint with Karachi Kin

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Xpvz Soil: An Unlikely Source of Nitrogen Oxide Pollution
It was only re颅l颅at颅ively re颅cently that tiny, single-celled thau颅marchaea were dis颅covered to ex颅ist and thrive in the pela颅gic ocean, where their pop颅u颅la颅tion size of roughly 1028 (10 bil颅lion quin颅til颅lion) cells makes them one of th nike dunk donna e most abun nike dunk high d颅ant or颅gan颅isms on our planet. A team of re颅search颅ers from the Bio颅logy Centre Czech Academy of Sci颅ences (Bud颅weis, Cze颅chia), MARUM 鈥?Cen颅ter for Mar颅ine En颅vir颅on颅mental Sci颅ences at the Uni颅versity of Bre颅men, and Max Planck In颅sti颅tute for Mar颅ine Mi颅cro颅bi颅o颅logy (Bre颅 dunk nike low men, Ger颅many) have es颅tim颅ated that these chemoauto颅trophs re颅cycle ap颅prox颅im颅ately 5 per cent of the car颅bon and phos颅phorus as颅sim颅il颅ated by mar颅ine al颅gae and re颅lease ter颅ra颅grams (1012 g) of dis颅solved or颅gan颅ics to the ocean in颅terior each year. These find颅ings are now pub颅lished in the journal Science Advances.The wide颅spread suc颅cess of mar颅ine thau颅marchaea arises largely from their abil颅ity to con颅vert trace con颅cen颅tra颅tions of am颅mo颅nia to ni颅trite, which Known to call a spade a spade, veteran actor Rishi Kapoor has pulled up authorities for confusing filmmakers on the issue of casting Pakistani actors post Uri attacks.In a candid interview, Bollywood's "Chintoo Uncle" said it was unfair to suddenly ban artists from Pakistan and there should be a cut-off date on such issues聽for film productions to fall in line.The Indian Motion Picture Producers' Association (IMPPA) had banned Pakistani actors, singers and tec ugg fellboots hnicians from working on Indian films in the wake of woresening Indo-Pak ties.Rishi Kapoor stanley online shop reveals why he turned down role in Pakistani film"Films are not planned in one or three days. It takes time. You can't say that you're goi adidas campus beige ng to ban a picture," said聽Kapoor, who acted alongside聽Pakistan star Fawad Khan in his last hit Kapoor & Sons."You've been working for the last six months. These are unfair rulings and bullying tactics. You must give a cut-off period. It gives us time to finish our films and henceforth we will not take

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Mwtl Scientist Awarded Inaugural Antonio M. Gotto Jr. Prize
The gut contents of ancient Japanese people weren鈥檛 too dissimilar from the gut contents of their modern descendants, according to new research.After analyzing DNA remnants preserved in ancient human coprolites (fossilized feces), the researchers discovered that many of the long-dead bacteria and viruses found in the feces were the same species thriving in present-day Japanese guts.The research was published in PLOS yeezy 700 One. Gut reactionsThe researchers 鈥?from Japan鈥檚 National Institute of Genetics, the University of Tokyo and the Wakasa History Museum 鈥?sampled four coprolites taken from an archeological site in the Fukui Prefecture. The fossilized feces were estimated to have been 鈥渓eft鈥?by people living in the region 7,000-5,500 years ago, durin yeezy g Japan鈥檚 J艒mon period.Despite the degradation of the material, much of the DNA retained in the coprolites was extracted and sequenced at specia nike dunk lized labs at Kitasato University and the University of Tokyo. After comparing the ancient DNA sequenc BANGKOK:The systematic persecution of minority Muslims is on the rise across Myanmar and not confined to the northwestern state of Rakhine, where recent violence has sent nearly 90,000 Muslim newbalance Rohingya fleeing, a Myanmar rights gr stanley-cup oup said on Tuesday.The independent Burma Human Rights Network said that persecution was backed by the government, elements among the country's Buddhist monks, and ultra-nationalist civilian groups.Malala condemns suffering of Rohingya Muslim ugg boots tasmania s"The transition to democracy has allowed popular prejudices to influence how the new government rules, and has amplified a dangerous narrative that casts Muslims as an alien presence in Buddhist-majority Burma," the group said in a report. The report draws on more than 350 interviews in more than 46 towns and villages over an eight-month period since March 2016.Myanmar's government made no immediate response to the report. Authorities deny discrimination and say security forces in Rakhine are fighting a legitimate campaign

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Nmtv GeneBio and Genedata Integrate Computational Platforms to Support Proteomics Projects
A mysterious form of cell death, coded in proteins and enzymes, led to a discovery by UNC researchers uncovering a prime suspect for new cancer drug development.CIB1 is a protein discovered in the lab of Leslie Parise, PhD, professor and chair of the Department of Bioch nike high dunk emistry at the University of North Carolina School of Medicine. The small calcium binding protein is found in all kinds of cells.Cassandra Moran new balance , DO, was a pediatric oncology fellow at UNC prior to accepting a faculty position at Duke University. She is interested in neuroblastoma, a deadly form of childhood brain cancer. While working in the Parise lab at UNC as a resident, s adidas yeezys he found that decreasing CIB1 in neuroblastoma cells caused cell death.Cancer is a disease of uncontrolled cell growth, so the ability to cause cancer cell death in the lab is exciting to researchers 鈥?but the UNC team couldn鈥檛 figure out how it was happening.Tina Leisner, PhD, a UNC research associate in biochemistry, picked up where Dr. Moran left LAHORE:There is a need to adopt the trait of 鈥榗ollectivism鈥?for the betterment of Pakistan as the practice of 鈥榠ndividualism鈥?in politics has damaged the country, said Punjab Chief Minister Shehbaz Sharif.Man seeks treason case against Punjab CM Shehbaz SharifIn a statement issued to the media on Tuesday, he said that everyone would have to work together for the well-being of the public and prosperity of the country. 鈥淧akistan is the motherland for all of us and we should work collectiv adidas samba adidas ely to make it a better place to live.鈥漈he chief minister said that it was adidas samba beige not the time to indulge in any disunity; but rather remain united. 鈥淚t is unwise to politicise development projects of national importance as all th adidas samba ese projects were meant for public benefit. Projects should move forward so that people benefit from such initiatives.Shehbaz said the Pakistan Muslim League-Nawaz government had always promoted tolerance, civility and national unity because Pakistan could be become a harbinger of peac

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Rwol Shaharyar Khan receives green signal from PM to continue as PCB chief
ProMetic Life Sciences Inc. has announced that it has received a $4.6 million purchase order under its ongoing supply agreement with Octapharma, a leading, Swiss based, independ dunk nike high ent global plasma fractionation company that specializes in human proteins.Shipments to Octapharma in relation to this order are expected to exceed $2.0 million during the second half of 2012.This latest order relates to the purchase of PrioClear鈩? a proprietary prion capture resin incorporated into Octapharma's manufacturing process for its solvent/detergent treated plasma product, Octaplas鈩G.Octaplas鈩G is currently approved for marketing in several European countries and the object of ongoing procedures for its regulatory approval for the North American market."This larger than originally anticipated purchase order from Octapharma for the second half dunk nike low of 2012 demonstr yeezy 350 ates the industry's growing demand for safer and differentiating plasma derived products", said Pierre Laurin, President and Chief Executive Off KARACHI:The Sindh High Court (SHC) directed on Friday Pakistan Peoples Party's (PPP) Faryal Talpur, Ayaz Soomro and others to f new balance ile comments on a petition seeking a probe into alleged misappropriation of the Prime Minister's Development Scheme funds meant for Larkana.A division bench, headed by Justice Aqeel Ahmed Abbasi, directed the PPP leaders, the Larkana deputy commissioner and others to file comments by March 24.A resid newbalance 990 ent of Larkana, Bashir Ahmed, had taken the PPP lawmakers and others to court over an alleged misappropriation of development funds.The petitioner said in 2008 th adidas campus gr眉n e then prime minister had announced a scheme titled 'Development and Beautification of Larkana City' and funds worth Rs12 billion were allocated for it. He claimed that the funds were released but no work had been done in the city.He alleged that a huge amount of public money had been misappropriated and plundered, therefore, the same may be investigated and those found responsible should be taken to task.O

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Ngkg Bangladesh upholds miltant tycoon;s death sentence
deCODE biostructures, In nike high dunk chas announced that it successfully met a development milestone under its agreemen dunks nike low t withInterMune via delivery of multiple small molecule fragments to a proprietary protein target.The structures represent chem nike dunk high otypes and provide new scaffolds for developing unique small molecule drugs. In connection with the achievement of this milestone, deCODE and InterMune agreed to extend their collaborative research agreement. ISLAMABAD:The Securities and Exchange Commission of Pakistan (SECP) has approved the first application filed by a non-banking finance company (NBFC) under the newly promulgated Private Fund Regulations 2015 for undertaking private equity and venture capital fund management services.The licence will allow Lakson Investments Limited to launch private equity and venture capital funds as well as alternative funds.鈥淭he licence is the first step for the regulation of priva adidas campus bianche te pools of capital that are raised locally for deployment by various types of investment funds,鈥?the SECP said in a statement.It will facilitate the raising of funds from high net-worth investors through different types of funds like private equity funds, infrastructure funds, hedge funds, debt funds, et nb 993 c.According to the prevalent regulatory requirement, the private equity and venture capital funds should be established in a closed-end new balance uomo structure for investment in securities of an unlisted company or a company listed on th

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Fdnn Guarding Against Cancer
In a paper to be published in Current Pharmaceutical Design, six scientists from the US and Europe, including Dr PennySparrow from the John Inn yeezy damen es Centre, compare risk assessment and regulation between the two continents. Sense About Science will yeezy slides run a live Q&A on the subject from 12-1 on Wednesday 20th February.In the EU, plant-made pharmaceuticals have to be authorised in the same way as GM agricultural crops. In theory, agricultural crops can be grown by any farmer in the EU once approved. But for crops producing pharmaceuticals this would never actually happen. Drug companies would likely license farmers to grow these crops under controlled, defined and confined conditions.鈥淲e need tight regulations enforced by continuous o dunk nike low versight to encourage investment, while maintaining trust,鈥?said Dr Penny Sparrow from the John Innes Centre.鈥淭his will be of high importance, especially in Europe, where the issues surrounding the cultivation of GM agricultural crops remains a contentious con Pakistani boxer Muhammad Waseem said on Sunday that he is thankfu stanley-cup l to Balochistan traffic police for their constant support throughout his career.Waseem, who arrived in Quetta today after successfully defending his World Boxing Council (WBC) Silver flyweight title in Seoul, South Korea last month, spoke about how the local authorities have always given him a protocol.鈥淚 would not only like to thank people who backed me and prayed for me, but also I would also like to thank Balochistan traffic police who always come to the airport to receive me,鈥?he said while speaking to the media.Muhammad Waseem successfully defends WBC Silver flyweight titleThe 29-year-old added: 鈥淭hey adidas campus beige have always given me this adidas campus rosa protocol.鈥漈he Quetta-born also revealed that he still receives financial support from his South Korean promoters for his professional boxing bouts. He added that despite talks of support from the government, nothing has materialised yet.WBC Silver flyweight champion: Waseem ready for first tit

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Lwbv Horoscope: August 21, 2016
Nanomaterials scientists from Utrecht University have improved a nanogel in such a way that it can now transport individual molecules from one liquid to the other. 鈥淏y enlarging the surface area between two liquids, we can increase the exchange of chemicals. This technique can make industrial processes more energy efficient and open possibilities to make better solar cells.鈥?The researchers鈥?paper was recently published by the scientific magazine Advanced Materials. converse all star Physical Chemist Martin Haase and his research group work on techniques to make so-called bijels: emulsions of two liquids that do not mix, like oil and water, separated by an ultra-thin layer of nanoparticles that stabilizes the surface between the fluids. 鈥淚n such gel-like materials, two repellent liquids are interwoven鈥? Haase explains. 鈥淎t the interface of the two, molecules can move from one liqu air forces id to the other through the nanolayer.鈥漈he gels work best if the interface between yeezy the two liquids has a large surface. Haase PESHAWAR:The Pakistan Academy of Letters (PAL) held a two-day literary co stanley cups nference where speakers highlighted various aspects of Pakistani literature and its role in their research papers and stressed the need for national cohesion through literature.They urged the literati to play their due role to spread the message of pe adidas campus grau ace and tolerance, cultural diversity towards a pluralistic society.Poets and writers should promote a soft image of the country, they said.Delegates from across the country participated in the conference and read out papers on the role of literature in the national integration.PAL Chairman Dr Mohammad Qasim Bughio, while chairing the event, said that the basic objective of the conference was to provide a joint platform to the writers from all over the country to share their ideas on national integration. He said that writers Federally Administrated Tribal samba og adidas Area (Fata) would be given additional incentives including monthly stipends and an insurance policy.Published in

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Cisbio Bioassays, a member of IBA air force 1 group and global developer of HTRF庐 (Homogeneous Time-Resolved Fluorescence) technology an nike jordan4 d servicesused in assay development and drug screening, today announced that it has extended its Tag-lite鈩?cell surface receptor platform with the introduction of a comprehensive catalogue of ligands and plasmids. The new catalogue marks the next step in the company鈥檚 development of a complete array of tools for G-Protein Coupled Receptor (GPCR) investigation and, more specifically, of Tag-lite, its homogeneous and non-radioactivea ciabatte yeezy lternative for the study of cell surface receptor dimerization and ligand binding. PARIS:Monaco ruined Paris Saint-Germain's Ligue 1 title celebrations as a clinical second-half performance gave the principality side a 2-0 victory at the Parc des Princes on Sunday.PSG w stanleycup rapped up a fourth consecutive league title in record time with eight matches to spare by thrashing Troyes 9-0 a week ago, but they were uncharacteristically flat in the capital.After a drab opening 45 minutes it was the visitors who adidas campus 80s turned on the style, as Vagner Love's fourth goal for the club gave them a deserved 65th-minute lead.Little Afghan Messi fan still keen to meet idolA David Luiz error gave Monaco a penalty that was coolly converted by Fabinho just three minutes later, as PSG slumped to just a second league defeat of the season, and a first at home since May 2014.The victory is a timely one for Le boots kaufen onardo Jardim's Monaco in the race for the top three and the Champions League, as they stay second in the table and now have the cushion of a six-point gap back to fourth-placed Lyon."This is a ver

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Jqon Drug Shows Unexpected Efficacy Against Aggressive Cancers
Horizon Discovery Group plc and ArcherDX, Inc. have announced that they have signed an Original Equipment Manufacture (OEM) agreement that will see Horizon鈥檚 Reference Materials supplied as a standa yeezy lone product alongside ArcherDX鈥檚 Archer鈩?dunk low mujer FusionPlex鈩?to aid customer validation of its ALK fusion assay kits.The agreement is a further endorsement of the demand in the translational sequencing market for accurate and reliable reference material to validate sample testing. Horizon鈥檚 reference materials will be available for sale alongside Archer鈩?FusionPlex鈩?ALK fusion new balances 530 tests that can run on both Illumina庐 and Ion Torrent鈩?next-generation sequencing platforms, a fast-growing market that represented $2.5 billion in 2014 and Horizon anticipates that the Archer assay will prove to be well received by the market. Further financial details of the deal were not disclosed.The Archer鈩?FusionPlex鈩?ALK, RET, ROS1 Panel simultaneously detects and identifies both known and previously unidentified fusion ISLAMABAD:As a standoff persists between police and some of Islamabad鈥檚 lawyers after the latter had beaten up a police officer and tore his uniform in a district courtroom on Saturday, police on Tuesday sought the suspension of licences and other punitive measures against the group of lawyers involved.Around a dozen lawyers on Saturday had assaulted ASI Javed Sultan of Margalla police as he testif uggs hausschuhe ied before a judge. He was beaten up and humiliated inside as well as outside the courtroom of Judicial Magistrate Jawad Hussain Adil.The lawyers who attacked him were angry because he had impounded an undocumented motorbike of a lawyer a few nights earlier on newbalance March 15.Though the police had booked at least four named and 20 unidentified lawyers for assaulting Sultan, they did not arrest adidas samba uomo the suspects since the lawyers鈥?bodies rallied behind the suspected lawyers while some secured pre-arrest bail.The police on Tuesday wrote a letter to judges of the Islamabad district court, the district and h

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Fuel Mazari vs Asif: Court issues preadmission notices to Sadiq, three ministers
There鈥檚 good news for women with multiple sclerosis (MS)鈥攔esearchers asics outlets now say the disease may not flare up again right after pregnancy as they had long believed, according to a preliminary study released today that will be presented at the American Academy of Neurology鈥檚 71st Annual Meeting in Philadelphia, May 4 to 10, 2019. Most people with MS have the relapsing-remitting form of the disease, where symptoms flare up, then go into periods of remission.鈥淭hese results are e yeezys xciting, as MS is more common among women of childbearing age than in any other group,鈥?said study author Annette Langer-Gould, MD, PhD, of Kaiser Permanente Southern California in Pasadena, Calif., and a member of the American Academy of Neurology. 鈥淭his shows us that women with MS today can have children, breastfeed and resume the yeezy 700 ir treatment without experiencing an increased risk of relapses during the postpartum period.鈥滾anger-Gould said the information on an increased risk of relapse after pregnancy was determined ISLAMABAD:More than 770 policemen, along with FC personnel, will provide security to vaccination teams during the upcoming anti-polio drive in Islam adidas sneakers campus abad. According to directives from the police top brass, all zonal SPs would personally supervise security duties in their respective areas. Owing to fatal adidas campus 00's attacks on polio workers in the past, I stanleycup GP Tariq Masood Yasin directed SSP Operations Sajid Kiani to devise a comprehensive security plan for the inoculation teams.Published in The Express Tribune, March 9th, 2017.

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Eegr Software star Google expected to flex hardware muscle
The last few decades have seen impressive progress in laser-based technologies, which have led to significant advancements in atomic and molecular physics. The development of ultrashort laser pulses now allows scientists to study extremely fast phenomena, like charge transport in molecules and yeezys elementary steps of chemical reactions. But beyond that, our ability to observe such processes on the attosecond scale (one quintillionth of a second) means that it is also possible to baskets yeezy steer and probe the dynamics of individual electrons on their natural timeframes.One of the emerging ultrafast technologies is attosecond transient absorption spectroscopy (ATAS), which can track the movement of electrons at a specific site of a molecule. This is a particularly appealing feature of ATAS, because it permits tracing the evolution of the molecular system with spatial resolution at the nike dunk low atomic scale.Modern lasers can push chemistry into unexplored domains of light-matter interactions, where the role of KARACHI:Two Islamabad-based creative artists have displayed their work of art through pen and pencil, at Full Circle Gallery. The exhibition, which consists of sketches and pen work, is a combination of ugg boots f眉r damen randomness and intricacy.Hass nb zapatillas an Shah Gilani's work is at times pretty straightforward, with his simple geometrical designs, patterns or even lines. However, in some of the sketches displayed at the gallery, Gilani manages to create a level of complexity by bringing together all the various combinations. The self-trained artist agrees with the opinion that his abstract work does not fall in any category, nor can it be encapsulated in a single series of thought.For someone who has never been to an art school, no wonder Gilani is free and open in putting his heart, and not to forget his mind, on the paper. "I have been drawing for a long time and I never follow a certain point of view," said Gilani, talking to The Express Tribune. He believes that his work is open new balance 740 for interpretation and ha

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When high explosives were first invented, they were dangerous, unpredictable and could explode with even the slightest touch.Made from a mixture of gold, ammonia and chlorine, these explosives became notable for more than just their deadly potential 鈥?after detonating, they left behind a strange purple smoke unlike gunpowder or anything yeezy sneaker else seen at that time. More than nike dunk panda 400 years after the invention of 鈥渇ulminating gold鈥?explosives, scientists finally have an answer for why these compounds produce their iconic purple smoke. The research is published as a preprint in arXiv.From ancient alchemy to modern chemistryThe idea of a 16th century alchemist obsessed with their quest to turn lead into gold is an enduring trope in modern media, and for good reason. This fascination with 鈥渃hrysopoeia鈥? the artificial production of gold from more common metals, really happen new balance 550 ed. It gave way to one of the more revolutionary discoveries made in the 1500s 鈥?high explosives.The synthesis of fulminating g ISLAMABAD:In a historic attempt, mountaineers from Pakistan, Spain and Italy have managed to climb the feared Nanga Parbat for the first time in the winter season.鈥淎li Sadpara (Pakistan,) Alex T nb 574 xikon (Spain) and Simone Moro (Italy) have reached the top of Nanga Parbat,鈥?Karrar Haidri, a spokesman of the Alpine Clu adidas original campus b of Pakistan told AFP, confirming it was the first time the summit had been reached during winter months.A fourth climber, Tamara Lunger of Spain, stopped just short of the summit for reasons which were not immediately known.Climbers make first winter ascent of Pakistan's 'Killer Mountain' Nanga ParbatAt 8,126 metres (26,660 feet) Nanga Parbat is the world鈥檚 ninth highest mountain. It earned its grisly nickname of 鈥楰iller Mountain鈥?after more than 30 climbers died trying to conquer it before the first successful summit in 1953 in addition to claiming a number of mountaineers since. Along with K-2, Nanga Parbat was among the last of th adidas campus 80s e 14 eight-thousanders which had not been

[MethrenRoOrn]

Wthc Security guards for KKH trained by G-B police
DNA sequences obtained from a handful of patients with multiple sclerosis at the UCSF Medical Ce yeezy 700 nter have revealed the existence of an 鈥渋mmune exchange鈥?that allows the disease-causing cells to move in and out of the brain.The cells in question, obtained from spinal fluid and blood samples, are called B cells, which normally help to clear foreign infections from the body but sometimes react strongly with the body itself.One of the current theories of multiple sclerosis, which strikes hundreds of thousands of Americans and millions more worldwide, holds that the disease manifests when self-reactive B cells in the brain become activated and cause inflammation there.The apparent exchange of the cells between the brain and the blood may be a key to unlocking better treatments and d yeezy 350 iagnostics, because the activated B cells causing problems in the brain may be accessible whe air force n they move from the brain to the periphery.鈥淭he hope is that if we can identify culprit B cells, using precise tools, MADRID:Former world number one Roger Federer has pulled out of this week's Madrid Open with a back injury.The adidas sambarose Swiss great travelled to the Spanish capital for the tournament but was unable to practice on Monday and announced his withdrawal.Federer, however, said he would be back for the Rome Masters next week."I don't want to take more chances as I know I'm not going to be fully ready for Wednesday," he added, referring to his opening match."I would rather play it safe and rest up now and get ready for Rome. I' campus adidas m sorry to the tournament for coming and leaving without playing.Game adidas samba damen of throws: Big four to reunite in Madrid Masters"I arrived and I was okay and then I practised on Saturday and hurt my back a little bit and stopped early. I'm very disappointed to say the least," said Federer."I changed my schedule around and practised well in Switzerland before coming here."Federer said he was not worried about his preparations for the French Open that starts on May 22.High targets: Federer鈥檚

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Algp Antidepressant Based on Ketamine Gets Backing From FDA Advisory Group
Warnex Medical Laboratories, a division of Warnex Inc. and Epigenomics AG, announced the launch of Warnex's Septin9 blood testing service for colorectal cancer in Canada.Warnex's Septin9 test is based on Epigenomics' patented biomarker Septin9 and DNA methylation technologies. Warnex is the first laboratory to offer Septin9 testing in Canada, dunk nike store after obtaining the non-exclusive rights from Epigenomics in May 2010.Prior to its launch, Warnex's Septin9 test was independently developed and successfully validated using clinical blood samples from colorectal cancer patients and individuals with no apparent disease as verified by colonoscopy. yeezy 700 "We are pleased to add this asics colorectal cancer test based on real-time PCR technology to our service offering as part of our continued commitment to delivering the most advanced specialized diagnostic services to Canadian healthcare professionals," said Mark Busgang, President and CEO of Warnex."The Septin9 test is a convenient and specific blood test for c PESHAWAR:The long-standing issue involving the upgradation of teachers in the tribal belt has been resolved on the prime minister鈥檚 directives. However campus adidas , an official notification has yet to be issued.Prime Minister Nawaz Sharif issued directives after Governor Iqbal Zafar Jhagra raised the matter at the federal level. As a result, Finance Minister Ishaq Dar agreed to upgrade the status of teachers which will benefit over 20,000 teachers all over Fata.According to a handout issued on Wednesday, Jhagra had held meetings with the finance minister and minister for Ministry of State and Frontier Regions (Safron) and informed them about the importance and sensitivity of the matter.As per the document, the governor said efforts to provide better opportunities to students nb 550 in the trib stanley website al belt and to improve education sector in tribal region were under way.He said education was given top most priority and added education emergency in tribal areas was already announced.He urged teachers to play the